Christal Sohl, PhD

We strive to combat diseases such as cancer by probing mechanistic questions at the intersection of biochemistry, molecular biophysics, and cell biology. We explore how altered enzyme activity impacts human health using kinetic, structure/function, and cellular studies coupled with collaborative efforts employing metabolomic and lipidomic technologies. By understanding the molecular mechanisms of enzyme dysfunction, we can illuminate structure-function relationships, probe global cellular consequences of mutations, identify new drug targets, and develop platforms for targeted therapy.